Unless you have a real good amount of traffic, particularly traffic that is high-converting, Google AdSense is probably not the best option.
To make good money affiliate ads that are related to the topic/niche of your website will usually work better. They will almost always pay better than AdSense or the other similar types of advertising options.
AdSense usually needs a lot of traffic to make good money. If you have some good affiliate ads, you can make a lot more money but you will usually want to make sure that the ads closely relate to what your site is about.
I'd go affiliate advertising unless you have a large amount of targeted traffic.
Hope this helps.
Cheers, Dean